Nitrogen Gas is a viable and cost effective option in Pharmaceuticals Industries


Due to effect of its end product on human health and environment, pharmaceutical industries process their products with very precision and utmost care. Even a very minor ignorance can lead to a hazard. The pharmaceutical needs to be very precise about its product from its manufacturing to packaging and transportation. Oxygen in the atmospheric air reacts with the processing chemicals, leads to change in chemical composition of the drug manufactured which would become a threat to human life and will adversely affect the reputation of concerned manufacturing unit in terms of brand and turn over both.

Earlier there were several traditional method applied for the same, but with the advancement of technology Nitrogen gas has emerged as a leading source for pharmaceutical products for a broad range of applications. 

Few of them are as follows:




Drug manufacturing

Aseptic Packaging

Analytical testing

Filtration, Separation and Purification

Nitrogen gas plays an essential role in the pharmaceutical industry, with a broad range of applications ranging from packaging to fire suppression in an obviously volatile manufacturing environment. Nitrogen Gas Generators which are capable of producing Nitrogen gas at site can now provide purity levels equal to that of liquid nitrogen, helping pharmaceutical manufacturer’s lower costs without sacrificing quality or efficiency. 

Liquid nitrogen deliveries require that the gas be converted to a liquid for truck transport. Upon arrival, the liquid must then be converted back into a gas. This two-time transfer of states because of these filling points – loading into the transport vehicle at the nitrogen facility and unloading again at the pharmaceutical production facility – creates avoidable product waste, not to mention additional charges for delivery. The most important is the time taken in this all process, which is of more importance. 

Nitrogen gas, when delivered to a pharmaceutical manufacturing facility, must also be stored on-site prior to use, also creating additional unnecessary waste. Once inside a cooled tank, the loss is often an automatic 10 percent of the delivery volume. And, even with a good vacuum, the tank will lose a minimum of .4 percent of volume daily if internal pressures are allowed to build because the gas remains sedentary. Purging or releasing tank pressure only contributes additional waste as well. 

And consider this: while generating liquid nitrogen requires a tremendous amount of energy, about 90 percent of nitrogen end uses require it as a gas and not a liquid. The primary reason nitrogen is liquefied is for ease of transportation, so shifting to on-site nitrogen generation helps reduce energy costs and lower emissions associated with the facility’s daily operation. 

While liquid nitrogen delivery channels have traditionally provided greater product purity – an essential element in pharmaceutical production, MVS Engineering’s Nitrogen Generation technology has helped boost in situ Nitrogen Gas generation purity to close this gap. As a result, higher purities in On-Site Nitrogen generation are now comparable to the liquid product and, with proper instrumentation, can be measured to ppm levels of oxygen concentration. Large majority of pharmaceutical industry applications can be met within the 10 to five ppm levels that can be readily achieved with MVS Nitrogen Generator, MSH-model

Shifting to on-site nitrogen generation capabilities is just one way that pharmaceutical manufacturing facilities can achieve significant cost savings, with the added benefit of a lower carbon footprint to help lead the way as an environmental steward in the community.